Episode 65: Inherited Bleeding Disorders

In collaboration with

A PODCAST LECTURE BY Thomas DeLoughery

22/11/22


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SPEAKER Bio

Tom DeLoughery

Tom DeLoughery (Dee-low-ree) is a native Hoosier who graduated from Indiana State University one year after Larry Bird and received his MD at Indiana University School of Medicine. He did his internship at the University of California, Irvine before travelling to Oregon where he finished his internal medicine residency and hematology/oncology fellowship at Oregon Health & Science University (OHSU).

He is currently a Professor of Medicine, Pathology and Pediatrics in the Divisions of Hematology/Oncology and Laboratory Medicine at OHSU. His clinical interests are in iron deficiency, general hematology and coagulation, subjects on which he has written extensively. He has won numerous teaching awards and has given education sessions to national meetings of many professional societies. He was course director for the medical school Blood Course for ten years and remains active in teaching.

He also has an interest in the hematologic aspects of Wilderness Medicine and served six years on the board of directors of the Wilderness Medicine Society and chaired their research committee for four years and remains an active member. He is a Master of the American College of Physicians and is a Fellow of the Academy of Wilderness Medicine.



LECTURE SUMMARY

This talk goes over the most common causes of inhirted bleeding disorders.  There are two major types of hemophilia – deficiency in factor VIII and IX – which predominant occur in men.  Hemophilia A is deficiency of factor VIII and is the most common form of hemophilia treated with factor concentrate.  Hemophilia B is less common but treatment principles are the same.  There are multiple types of von Willebrand Disease as this is a complex molecular that both carries factor VIII and forms large multimers essential for platelet function.   Mild forms of vWD can be treated by desmopressin but von Willebrand factor is needed for more severe types.


LEARNING OBJECTIVES

Upon completion of this activity, you should be able to:

  • Understand the patterns of bleeding in hemophilia

  • Learn how to dose clotting factor for hemophilia

  • Understand the different types of von Willebrand Diseases and their treatments


FURTHER INFO

To watch the video, for free, click here.


Hannah BellHP2, HC3Comment